Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.35 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.35 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.35 |
| ▸ | RPS17 | P08708 | 1/20 | 0.35 |
| ▸ | RPSA | P08865 | 1/20 | 0.35 |
| ▸ | RPS2 | P15880 | 1/20 | 0.35 |
| ▸ | RPL35A | P18077 | 1/20 | 0.35 |
| ▸ | RPL7 | P18124 | 1/20 | 0.35 |
| ▸ | RPL17 | P18621 | 1/20 | 0.35 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.35 |
| ▸ | RPS3 | P23396 | 1/20 | 0.35 |
| ▸ | RPS12 | P25398 | 1/20 | 0.35 |
| ▸ | RPL13 | P26373 | 1/20 | 0.35 |
| ▸ | RPL10 | P27635 | 1/20 | 0.35 |
| ▸ | RPL12 | P30050 | 1/20 | 0.35 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633635 | 0.75 | TSHR (0.44) | HRH3ITGB3ITGA2BAOC3CYP2C9 | |
| Hydrochloric Acid SCHEMBL8838087 | 0.73 | ADRB2 (0.49) | HRH3ADRB2NCF1PLD1ITGB3 | |
| SCHEMBL8635510 | 0.71 | RPLP1 (0.39) | HRH3ADRB2NCF1PLD1RPLP1 | |
| SCHEMBL8631574 | 0.71 | HRH3 (0.54) | HRH3CYP19A1ADRB2NCF1PLD1 | |
| Hydrochloric Acid SCHEMBL8838031 | 0.68 | HRH3 (0.41) | HRH3ADRB2NCF1PLD1ITGB3 | |
| SCHEMBL8635654 | 0.68 | MAPT (0.44) | HRH3AOC3TSHR | |
| SCHEMBL8633965 | 0.68 | NPY2R (0.55) | HRH3ITGB3ITGA2BTSHR | |
| Hydrochloric Acid SCHEMBL8838195 | 0.67 | NPY2R (0.54) | HRH3ITGB3ITGA2BAOC3 | |
| SCHEMBL7401896 | 0.67 | HRH3 (0.62) | HRH3ADRB2NCF1PLD1ITGB3 | |
| SCHEMBL8701129 | 0.67 | HRH3 (0.48) | HRH3CYP19A1ADRB2NCF1PLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |