Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633635 | 0.83 | TSHR (0.44) | MAPTALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL8633965 | 0.74 | NPY2R (0.55) | MAPTALDH1A1KDM4ELMNATSHR | |
| Hydrochloric Acid SCHEMBL8838195 | 0.73 | NPY2R (0.54) | MAPTALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL8634059 | 0.72 | ITGB3 (0.44) | MAPTALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL4379063 | 0.72 | KDM4E (0.82) | MAPTALDH1A1KDM4EHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL8699382 | 0.72 | ITGB3 (0.43) | MAPTALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL8635651 | 0.71 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL8633823 | 0.70 | NCF1 (0.39) | MAPTALDH1A1KDM4EHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL8636989 | 0.70 | ABCB1 (0.48) | ALDH1A1KDM4EHRH3NPY2R | |
| SCHEMBL8700994 | 0.70 | AOC3 (0.41) | MAPTALDH1A1HSD17B10TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |