Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630170 | 0.92 | CDC7 (0.43) | PTGS2ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL8631027 | 0.92 | PTGS2 (0.42) | PTGS2ALDH1A1FPR1MAPTMEN1 | |
| SCHEMBL8635531 | 0.91 | PTGS2 (0.50) | PTGS2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8629982 | 0.91 | EDNRB (0.43) | PTGS2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8630021 | 0.89 | SMN1; SMN2 (0.49) | PTGS2ALDH1A1FPR1MAPTMEN1 | |
| SCHEMBL8631438 | 0.89 | CYP1A2 (0.46) | PTGS2ALDH1A1MAPTKMT2APTGDR2 | |
| SCHEMBL8629382 | 0.89 | ALDH1A1 (0.41) | PTGS2ALDH1A1MEN1KMT2APTGDR2 | |
| SCHEMBL8630525 | 0.87 | CCR4 (0.41) | PTGS2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8635571 | 0.86 | PTGDR2 (0.48) | PTGS2ALDH1A1FPR1MAPTMEN1 | |
| SCHEMBL8630980 | 0.86 | KMT2A (0.39) | PTGS2ALDH1A1FPR1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |