Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 6/20 | 0.36 |
| ▸ | F10 | P00742 | 7/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632287 | 0.91 | PTGS2 (0.42) | ARGHSRPTGS2PTGS1KDM4E | |
| SCHEMBL8631397 | 0.89 | PTGS2 (0.41) | ARF10PTGS2F2PRSS1 | |
| SCHEMBL8630545 | 0.89 | AR (0.38) | ARGHSRF10PTGS2F2 | |
| SCHEMBL8632230 | 0.87 | PTGS2 (0.37) | ARF10PTGS2F2PRSS1 | |
| SCHEMBL7778268 | 0.87 | PTGS2 (0.43) | ARGHSRPTGS2PTGS1 | |
| SCHEMBL8629873 | 0.85 | PTGS2 (0.41) | GHSRF10PTGS2F2PRSS1 | |
| SCHEMBL8633375 | 0.85 | F10 (0.37) | F10PTGS2F2PRSS1PRSS2 | |
| SCHEMBL8630040 | 0.83 | POLB (0.36) | F10PTGS2KDM4EHPGD | |
| SCHEMBL7777935 | 0.83 | PTGS2 (0.46) | ARGHSRPTGS2PTGS1 | |
| SCHEMBL8633055 | 0.81 | AR (0.39) | ARGHSRF10PTGS2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |