SCHEMBL8635703

SCHEMBL8635703

CCOc1ccc(Oc2ccc(O)c(C(C)C)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.58
THRA P10827 12/20 0.52
THRB P10828 12/20 0.52
TDP1 Q9NUW8 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
PTPN1 P18031 1/20 0.49
MAPT P10636 1/20 0.49
MAPK1 P28482 1/20 0.49
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.49
GAA P10253 1/20 0.49
TSHR P16473 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8636021 0.89 LTA4H (0.56) LTA4HTHRATHRBTDP1L3MBTL1
SCHEMBL1581472 0.88 THRA (0.58) THRATHRB
SCHEMBL8636369 0.83 THRA (0.55) THRATHRB
SCHEMBL8636953 0.81 THRA (0.50) THRATHRB
SCHEMBL8631679 0.81 THRB (0.51) THRATHRBTDP1L3MBTL1MEN1
SCHEMBL8633867 0.79 LTA4H (0.61) LTA4HTHRATHRBTDP1L3MBTL1
SCHEMBL7073286 0.78 THRA (0.48) THRATHRB
SCHEMBL7073284 0.78 THRB (0.51) THRATHRB
SCHEMBL10814812 0.78 THRA (0.49) THRATHRB
SCHEMBL8636430 0.78 LTA4H (0.59) LTA4HTDP1PTPN1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1080251-C Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use inproduct of said dihalopropene compounds SUMITOMO CHEMICAL CO (JP) 2002-03-06 CN disclosed
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed