Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581472 | 0.82 | THRA (0.58) | THRBTHRA | |
| SCHEMBL8635703 | 0.78 | LTA4H (0.58) | THRBTHRA | |
| SCHEMBL8636369 | 0.78 | THRA (0.55) | THRBTHRA | |
| SCHEMBL8636953 | 0.76 | THRA (0.50) | THRBTHRA | |
| SCHEMBL4351004 | 0.76 | THRB (0.54) | THRBTHRA | |
| SCHEMBL27666404 | 0.76 | THRA (0.59) | THRBTHRA | |
| SCHEMBL7073643 | 0.75 | THRA (0.49) | THRBTHRA | |
| SCHEMBL7073286 | 0.73 | THRA (0.48) | THRBTHRA | |
| SCHEMBL10814812 | 0.73 | THRA (0.49) | THRBTHRA | |
| SCHEMBL27713148 | 0.73 | THRA (0.61) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000008-B1 | NOVEL THYROID RECEPTOR LIGANDS AND METHOD | KAROBIO AB (SE) | 2003-06-25 | — | — | EP | disclosed |
| US-6465687-B1 | SUBSTITUTED 4-HYDROXY-3-ALKYL- OR CYCLOALKYL-PHENOXYBENZENE COMPOUNDS SUCH AS 3,5-DIBROMO-4-(4-HYDROXY-3-ISOPROPYLPHENOXY)BENZOIC ACID, EXPRESSION INHIBITION OF A T3 REGULATED GENE | KARO BIO AB (SE) | 2002-10-15 | — | — | US | disclosed |
| EP-1000008-A1 | NOVEL THYROID RECEPTOR LIGANDS AND METHOD | KARO BIO AB (SE) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999000353-A1 | NOVEL THYROID RECEPTOR LIGANDS AND METHOD | KARO BIO AB (SE) | 1999-01-07 | — | — | WO | disclosed |