Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634718 | 0.89 | POLB (0.37) | POLBCYP1A2GAACYP2D6CYP2C19 | |
| SCHEMBL8636720 | 0.85 | ACACB (0.37) | POLBCYP1A2GAACYP2D6CYP2C19 | |
| SCHEMBL8632153 | 0.82 | PLAU (0.35) | POLBCYP1A2GAACYP2D6CYP2C19 | |
| SCHEMBL8632744 | 0.78 | PLAU (0.35) | POLBPLAUHTTMAPTSMN1; SMN2 | |
| SCHEMBL8636445 | 0.74 | ACACB (0.38) | POLBCYP1A2GAACYP2D6CYP2C19 | |
| SCHEMBL8635590 | 0.74 | POLB (0.45) | POLBCYP1A2GAACYP2D6CYP2C19 | |
| SCHEMBL8635966 | 0.73 | THRB (0.39) | POLBCYP1A2GAACYP2D6CYP2C19 | |
| SCHEMBL8634698 | 0.73 | HTT (0.37) | CYP1A2GAACYP2D6CYP2C19HTT | |
| SCHEMBL8634567 | 0.72 | ADRA2A (0.37) | POLBCYP1A2GAACYP2D6CYP2C19 | |
| SCHEMBL8636137 | 0.72 | ACACB (0.36) | POLBCYP2D6HTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648729-B1 | Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound | SUMITOMO CHEMICAL CO (JP) | 1998-07-15 | — | — | EP | disclosed |
| US-5698702-A | INTERMEDIATES FOR INSECTICIDES, ACARICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-16 | — | — | US | disclosed |
| US-5530015-A | Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0648729-A1 | Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-04-19 | — | — | EP | disclosed |