SCHEMBL8636720

SCHEMBL8636720

CC(C)Oc1ccc(Oc2ccc(OCC=C(Cl)Cl)c(Br)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACB O00763 4/20 0.37
ACACA Q13085 4/20 0.37
PLAU P00749 1/20 0.37
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
PTGDR Q13258 2/20 0.33
MAPT P10636 1/20 0.33
ERN1 O75460 1/20 0.33
POLB P06746 2/20 0.32
THRB P10828 1/20 0.32
RORC P51449 1/20 0.32
CYP1A2 P05177 1/20 0.32
GAA P10253 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
ALDH1A3 P47895 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8636445 0.89 ACACB (0.38) ACACBACACAPLAUSMN1; SMN2NPC1
SCHEMBL8635830 0.85 POLB (0.36) PLAUHTTSMN1; SMN2NPC1RAB9A
SCHEMBL8635966 0.85 THRB (0.39) ACACBACACAHTTPTGDRPOLB
SCHEMBL8632153 0.84 PLAU (0.35) ACACBPLAUHTTSMN1; SMN2NPC1
SCHEMBL8632579 0.84 NPC1 (0.38) HTTSMN1; SMN2NPC1RAB9ALMNA
SCHEMBL8636137 0.84 ACACB (0.36) ACACBACACAHTTSMN1; SMN2RAB9A
SCHEMBL8635806 0.83 ACACB (0.36) ACACBACACAHTTPTGDRPOLB
SCHEMBL8638478 0.82 ACACB (0.35) ACACBACACAHTTPTGDRPOLB
SCHEMBL8632253 0.82 PPARG (0.40)
SCHEMBL8634403 0.82 FFAR4 (0.43) ACACBACACAHTTFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed