Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636323 | 0.89 | AGTR1 (0.40) | AGTR1AGTR2CHRM3TLR7APLNR | |
| SCHEMBL8635299 | 0.88 | AGTR1 (0.38) | AGTR1AGTR2CHRM3TLR7APLNR | |
| SCHEMBL8634862 | 0.87 | AGTR1 (0.35) | AGTR1AGTR2CHRM3TLR7 | |
| SCHEMBL8639183 | 0.81 | AGTR2 (0.42) | AGTR1AGTR2 | |
| SCHEMBL8636030 | 0.80 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL8636053 | 0.78 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL7839345 | 0.68 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL8636318 | 0.68 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL8633071 | 0.68 | AGTR2 (0.43) | AGTR1AGTR2APLNR | |
| SCHEMBL8635295 | 0.67 | AGTR1 (0.46) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776964-A | HYPOTENSIVE AGENTS; ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-07 | — | — | US | disclosed |