SCHEMBL8634403

SCHEMBL8634403

CC(C)Oc1ccc(Oc2ccc(OCC=C(Cl)Cl)c(C(F)(F)F)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 4/20 0.43
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
RXRG P48443 1/20 0.37
ACACB O00763 1/20 0.35
ACACA Q13085 1/20 0.35
PPARG P37231 1/20 0.34
PPARD Q03181 1/20 0.34
PPARA Q07869 1/20 0.34
AR P10275 8/20 0.34
HTT P42858 1/20 0.34
AAK1 Q2M2I8 1/20 0.33
CETP P11597 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8635499 0.92 FFAR4 (0.43) FFAR4RXRARXRBRXRGPPARG
SCHEMBL8631843 0.88 FFAR4 (0.39) FFAR4RXRARXRBRXRGACACB
SCHEMBL8633073 0.87 L3MBTL1 (0.39) ARHTT
SCHEMBL8635048 0.86 MAPT (0.44) RXRARXRBRXRGARHTT
SCHEMBL8636474 0.85 RXRA (0.38) RXRARXRBRXRGPPARGPPARD
SCHEMBL8634174 0.85 AR (0.39) FFAR4PPARGPPARDPPARAAR
SCHEMBL8635276 0.85 ALDH1A1 (0.36) FFAR4ARHTT
SCHEMBL8632518 0.85 MAPT (0.39) RXRARXRBRXRGPPARGPPARD
SCHEMBL8636074 0.84 KDM4E (0.37) PPARAARHTT
SCHEMBL8633864 0.84 MAOB (0.36) PPARGPPARDPPARAARHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP claimed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US claimed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP claimed
JP-7188088-A None JP disclosed
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
JP-H07188088-A DIHALOPROPENE COMPOUND, INSECTICIDE AND ACARICIDE CONTAINING THE SAME COMPOUND AS ACTIVE INGREDIENT AND INTERMEDIATE FOR PRODUCING THE SAME COMPOUND SUMITOMO CHEM CO LTD 1995-07-25 JP disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed