SCHEMBL8636209

SCHEMBL8636209

CCOc1ccc(Oc2ccc(OCc3ccccc3)c(C(F)(F)F)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.50
AR P10275 3/20 0.47
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PPARG P37231 2/20 0.45
PSEN1 P49768 2/20 0.45
ALOX5 P09917 1/20 0.45
MRGPRX4 Q96LA9 6/20 0.44
RXRA P19793 3/20 0.43
RXRB P28702 3/20 0.43
RXRG P48443 3/20 0.43
PPARD Q03181 1/20 0.42
PPARA Q07869 1/20 0.42
TP53 P04637 1/20 0.41
PKM P14618 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL753616 0.82 MAOB (0.54) MRGPRX4RXRARXRBRXRG
SCHEMBL8557138 0.81 MRGPRX4 (0.44) LTA4HARMRGPRX4RXRARXRB
SCHEMBL27531729 0.79 LTA4H (0.57) LTA4HARLMNAMAPTATM
SCHEMBL8635247 0.79 LTA4H (0.53) LTA4HLMNAATML3MBTL1PPARG
SCHEMBL11324524 0.79 LTA4H (0.74) LTA4HLMNAMAPTL3MBTL1PPARG
SCHEMBL2868493 0.78 LTA4H (0.51) LTA4HLMNAMAPTATMPPARG
SCHEMBL14453588 0.76 MRGPRX4 (0.50) MAPTL3MBTL1MRGPRX4RXRARXRB
SCHEMBL20756090 0.75 RXRA (0.54) LTA4HARMAPTL3MBTL1MRGPRX4
SCHEMBL8635048 0.75 MAPT (0.44) LTA4HARLMNAMAPTATM
SCHEMBL8638264 0.75 LMNA (0.44) LTA4HARLMNAMAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1080251-C Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use inproduct of said dihalopropene compounds SUMITOMO CHEMICAL CO (JP) 2002-03-06 CN disclosed
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
CN-1108642-A Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use inproduct of said dihalopropene compounds SUMITOMO CHEMICAL CO (JP) 1995-09-20 CN disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed