Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636260 | 0.78 | SPHK1 (0.35) | HRH3RORCSPHK1ITGB3ITGA2B | |
| SCHEMBL8634075 | 0.77 | RORC (0.45) | RORC | |
| SCHEMBL8633897 | 0.70 | HRH3 (0.35) | HRH3ITGB3ITGA2BCHRM1 | |
| SCHEMBL8636978 | 0.67 | ITGB3 (0.41) | RORCSPHK1ITGB3ITGA2BCHRM1 | |
| SCHEMBL8636259 | 0.66 | NPY2R (0.35) | OPRM1HRH3NPY2RABCB1ITGB3 | |
| Hydrochloric Acid SCHEMBL8837964 | 0.66 | ITGB3 (0.45) | HRH3ITGB3ITGA2B | |
| SCHEMBL22751990 | 0.64 | CHKA (0.47) | OPRM1HRH3ITGB3ITGA2B | |
| SCHEMBL8702205 | 0.64 | L3MBTL1 (0.42) | RORCITGB3ITGA2BL3MBTL1 | |
| SCHEMBL8681189 | 0.61 | ITGB3 (0.42) | HRH3NPY2RTP53ITGB3ITGA2B | |
| SCHEMBL8635011 | 0.61 | ITGB3 (0.48) | OPRM1HRH3ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |