Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637021 | 0.78 | HPGD (0.39) | CA2HPGDEPHX2 | |
| SCHEMBL9010367 | 0.77 | FKBP1A (0.40) | F2FKBP1AEPHX2 | |
| SCHEMBL8636310 | 0.74 | HPGD (0.49) | F2CA2HPGDEPHX2 | |
| SCHEMBL28194907 | 0.73 | ALDH1A1 (0.53) | F2FKBP1ACA2HPGDNPC1 | |
| SCHEMBL8634918 | 0.71 | HPGD (0.51) | F2CA2HPGDEPHX2 | |
| SCHEMBL8396001 | 0.71 | FBP1 (0.48) | F2CA2 | |
| SCHEMBL28841579 | 0.69 | HPGD (0.53) | CA2HPGDEPHX2NPC1 | |
| SCHEMBL4682506 | 0.69 | KMT2A (0.44) | F2 | |
| SCHEMBL4681369 | 0.69 | KMT2A (0.46) | F2 | |
| SCHEMBL9053748 | 0.68 | FBP1 (0.45) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776964-A | HYPOTENSIVE AGENTS; ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-07 | — | — | US | disclosed |