SCHEMBL8636474

SCHEMBL8636474

FC(F)(F)c1ccc(Oc2ccc(OCC=C(Cl)Cl)c(C(F)(F)F)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
RXRG P48443 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
ATM Q13315 1/20 0.38
PPARD Q03181 2/20 0.37
MAOB P27338 2/20 0.37
AOC3 Q16853 1/20 0.37
AR P10275 2/20 0.36
SLC6A4 P31645 2/20 0.36
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
FFAR1 O14842 2/20 0.36
ALOX5 P09917 1/20 0.36
PPARG P37231 1/20 0.36
PSEN1 P49768 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8632518 0.91 MAPT (0.39) RXRARXRBRXRGL3MBTL1LMNA
SCHEMBL8634961 0.91 RXRA (0.35) RXRARXRBRXRGL3MBTL1LMNA
SCHEMBL8634174 0.90 AR (0.39) PPARDMAOBAOC3ARALOX5
SCHEMBL8633081 0.89 MAOB (0.43) RXRARXRBRXRGL3MBTL1MAOB
SCHEMBL8636074 0.89 KDM4E (0.37) MAPTARRAB9A
SCHEMBL8633073 0.89 L3MBTL1 (0.39) L3MBTL1LMNAMAPTATMAR
SCHEMBL8633864 0.89 MAOB (0.36) PPARDMAOBAOC3ARSLC6A4
SCHEMBL8635775 0.88 MAPT (0.45) L3MBTL1LMNAMAPTATMPPARD
SCHEMBL8638861 0.88 AR (0.38) MAPTPPARDMAOBAOC3AR
SCHEMBL8635048 0.88 MAPT (0.44) RXRARXRBRXRGL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed