SCHEMBL8633864

SCHEMBL8633864

FC(F)(F)Oc1ccc(Oc2ccc(OCC=C(Cl)Cl)c(C(F)(F)F)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.36
AOC3 Q16853 1/20 0.36
AR P10275 3/20 0.36
SLC6A4 P31645 5/20 0.35
SLC6A2 P23975 4/20 0.35
MAPK8 P45983 1/20 0.35
MAPK10 P53779 1/20 0.35
PPARD Q03181 3/20 0.33
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33
MMP14 P50281 1/20 0.33
HTT P42858 1/20 0.33
PPARA Q07869 3/20 0.33
SLC6A3 Q01959 2/20 0.33
RAF1 P04049 1/20 0.33
EPHX2 P34913 1/20 0.33
CETP P11597 1/20 0.33
PPARG P37231 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8636474 0.89 RXRA (0.38) MAOBAOC3ARSLC6A4PPARD
SCHEMBL8634174 0.89 AR (0.39) MAOBAOC3ARPPARDPPARA
SCHEMBL8636074 0.88 KDM4E (0.37) ARHTTPPARA
SCHEMBL8633073 0.88 L3MBTL1 (0.39) ARMAPK8MAPK10HTTEPHX2
SCHEMBL8635048 0.86 MAPT (0.44) ARMAPK8MAPK10HTT
SCHEMBL8638861 0.86 AR (0.38) MAOBAOC3ARPPARDPPARA
SCHEMBL8632518 0.85 MAPT (0.39) MAOBAOC3ARPPARDHTT
SCHEMBL8636008 0.85 AR (0.38) ARSLC6A4PPARD
SCHEMBL8635779 0.85 AR (0.39) MAOBAOC3ARPPARDHTT
SCHEMBL8634961 0.85 RXRA (0.35) ARPPARDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed