Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 3/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8347396 | 0.86 | TACR2 (0.48) | TACR2TACR1HRH1 | |
| SCHEMBL8636699 | 0.84 | SPR (0.40) | TACR2SLC6A9TACR1 | |
| SCHEMBL8355974 | 0.82 | CA12 (0.42) | ALDH1A1GAASMN1; SMN2TACR2TACR1 | |
| SCHEMBL8350132 | 0.81 | TACR2 (0.53) | TACR2TACR1HRH1 | |
| SCHEMBL8350410 | 0.81 | KMT2A (0.38) | TACR2TACR1HRH1 | |
| SCHEMBL8355501 | 0.80 | TACR2 (0.51) | GAATACR2TACR1HRH1 | |
| SCHEMBL8348494 | 0.79 | TACR2 (0.50) | ALDH1A1TACR2TACR1 | |
| SCHEMBL8356065 | 0.79 | KMT2A (0.39) | ALDH1A1SMN1; SMN2TACR2TACR1 | |
| SCHEMBL8347573 | 0.79 | USP2 (0.43) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8349962 | 0.79 | TACR2 (0.50) | ALDH1A1GAATACR2TACR1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861416-A | TREATMENT OF ASTHMA OR COUGH | MERRELL PHARMACEUTICALS INC. (US) | 1999-01-19 | — | — | US | disclosed |
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |