Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | UBE2M | P61081 | 1/20 | 0.54 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351389 | 0.87 | ALDH1A1 (0.56) | ALDH1A1CYP1A2MEN1KMT2AKDM4E | |
| SCHEMBL8351152 | 0.84 | ALDH1A1 (0.64) | ALDH1A1CYP1A2MEN1KMT2AKDM4E | |
| SCHEMBL8638113 | 0.83 | LMNA (0.60) | ALDH1A1CYP1A2MEN1KMT2AKDM4E | |
| SCHEMBL8347627 | 0.82 | PDE4B (0.53) | ALDH1A1CYP1A2UBE2MDCUN1D1GAA | |
| SCHEMBL8640542 | 0.82 | PDE4B (0.56) | ALDH1A1CYP1A2UBE2MDCUN1D1GAA | |
| SCHEMBL8638632 | 0.81 | PDE4B (0.53) | ALDH1A1CYP1A2MEN1KMT2AKDM4E | |
| SCHEMBL724938 | 0.79 | ALDH1A1 (0.71) | ALDH1A1CYP1A2MEN1KMT2AKDM4E | |
| SCHEMBL8352641 | 0.78 | PDE4B (0.65) | KDM4EGAALMNA | |
| SCHEMBL8636998 | 0.78 | ALDH1A1 (0.65) | ALDH1A1CYP1A2HTTUBE2MDCUN1D1 | |
| SCHEMBL8350460 | 0.78 | ALDH1A1 (0.59) | ALDH1A1CYP1A2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |