Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | UBE2M | P61081 | 1/20 | 0.51 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351152 | 0.88 | ALDH1A1 (0.64) | PDE4BALDH1A1CYP1A2HSD11B1LMNA | |
| SCHEMBL8638316 | 0.87 | SCD5 (0.55) | PDE4BALDH1A1CYP1A2HTTTAAR1 | |
| SCHEMBL8347627 | 0.86 | PDE4B (0.53) | PDE4BALDH1A1CYP1A2LMNAUBE2M | |
| SCHEMBL8640542 | 0.86 | PDE4B (0.56) | PDE4BALDH1A1CYP1A2LMNAUBE2M | |
| SCHEMBL8355588 | 0.84 | KMT2A (0.54) | PDE4BALDH1A1CYP1A2LMNAHTT | |
| SCHEMBL8352641 | 0.84 | PDE4B (0.65) | PDE4BLMNAGAAKDM4E | |
| SCHEMBL8640754 | 0.83 | PDE4B (0.53) | PDE4BALDH1A1CYP1A2HTTTAAR1 | |
| SCHEMBL8636998 | 0.82 | ALDH1A1 (0.65) | PDE4BALDH1A1CYP1A2HSD11B1LMNA | |
| SCHEMBL8356221 | 0.82 | HTT (0.62) | ALDH1A1CYP1A2LMNAHTTTAAR1 | |
| SCHEMBL8636740 | 0.81 | ALDH1A1 (0.56) | ALDH1A1CYP1A2LMNAHTTUBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |