SCHEMBL1930745

SCHEMBL1930745

c1ccc(CO[SiH](c2ccc(Oc3ccccc3)cc2)c2ccc(Oc3ccccc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.46
NR1H2 P55055 1/20 0.45
BAX Q07812 1/20 0.45
TSHR P16473 2/20 0.44
SRD5A2 P31213 1/20 0.42
MAOA P21397 1/20 0.41
FFAR1 O14842 2/20 0.41
FFAR4 Q5NUL3 1/20 0.41
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
PTGS1 P23219 1/20 0.40
SLC6A2 P23975 1/20 0.40
CYP2C19 P33261 1/20 0.40
PTGS2 P35354 1/20 0.40
SLC6A3 Q01959 1/20 0.40
HIF1A Q16665 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
NR4A1 P22736 1/20 0.40
NR4A2 P43354 1/20 0.40
NR4A3 Q92570 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL863694 0.84 TSHR (0.50) TSHRMAOALMNACYP1A2PTGS1
SCHEMBL1930746 0.79 SLC6A2 (0.41) LTA4HTSHRLMNASLC6A2
SCHEMBL3296792 0.76 LTA4H (0.57) LTA4HNR1H2BAXTSHRSRD5A2
SCHEMBL11849334 0.74 LMNA (0.69) LTA4HMAOAFFAR1FFAR4LMNA
Diphenylether SCHEMBL27567755 0.73 TSHR (0.75) LTA4HNR1H2BAXTSHRMAOA
SCHEMBL19784955 0.72 LTA4H (0.58) LTA4HNR1H2BAXTSHRSRD5A2
SCHEMBL5538712 0.71 LMNA (0.72) LTA4HMAOAFFAR1FFAR4LMNA
SCHEMBL8994543 0.71 TSHR (0.64) LTA4HNR1H2BAXTSHRSRD5A2
SCHEMBL1930451 0.71 LTA4H (0.50) LTA4HNR1H2BAXTSHRSRD5A2
SCHEMBL27757762 0.71 LTA4H (0.56) LTA4HNR1H2BAXTSHRSRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2019106-B1 (Thio)Phenoxy Phenyl Silane Composition And Method For Making Same ROHM & HAAS (US) 2013-11-27 EP disclosed
US-7956125-B2 (Thio)phenoxy phenyl silane compostion and method for making same ROHM AND HAAS COMPANY (US) 2011-06-07 US disclosed
US-20090039313-A1 (Thio)phenoxy phenyl silane compostion and method for making same ROHM AND HAAS COMPANY (US) 2009-02-12 US disclosed
EP-2019106-A1 (Thio)Phenoxy Phenyl Silane Composition And Method For Making Same Rohm and Haas Company (US) 2009-01-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090039313-A1 (Thio)phenoxy phenyl silane compostion and method for making same TPMT, TTR, TST LTA4H 671/4885NR1H2 3713/4885BAX 3881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.