Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8638777 | 0.91 | MAOA (0.38) | ESR1ESR2KMT2A | |
| SCHEMBL9173014 | 0.86 | MAOB (0.35) | MAPTKMT2A | |
| SCHEMBL6436979 | 0.86 | ALDH1A1 (0.36) | MAPTALDH1A1RAB9AKMT2A | |
| SCHEMBL8635639 | 0.86 | CASP1 (0.39) | ALDH1A1RAB9AKMT2A | |
| SCHEMBL8635721 | 0.85 | HPGD (0.39) | ALDH1A1KMT2A | |
| SCHEMBL8639858 | 0.83 | ALDH1A1 (0.37) | MAPTALDH1A1 | |
| SCHEMBL8653036 | 0.83 | CASP3 (0.34) | MAPT | |
| Sinitrodil SCHEMBL503115 | 0.83 | TSHR (0.34) | MAPTALDH1A1RAB9A | |
| Sinitrodil SCHEMBL31066546 | 0.83 | TSHR (0.34) | MAPTALDH1A1RAB9A | |
| SCHEMBL8638798 | 0.82 | KCNH2 (0.35) | ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480882-A | Benzoxazinone and benzothiazinone derivatives having cardiovascular activity | ITALFARMACO S.P.A. (IT) | 1996-01-02 | — | — | US | claimed |
| EP-0566018-B1 | Benzoxazinone and benzothiazinone derivatives endowed with cardiovascular activity | ITALFARMACO SPA (IT) | 1998-08-05 | — | — | EP | disclosed |
| US-5480882-A | Benzoxazinone and benzothiazinone derivatives having cardiovascular activity | ITALFARMACO S.P.A. (IT) | 1996-01-02 | — | — | US | disclosed |
| EP-0566018-A2 | Benzoxazinone and benzothiazinone derivatives endowed with cardiovascular activity | ITALFARMACO S.p.A. (IT) | 1993-10-20 | — | — | EP | disclosed |