Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636724 | 0.77 | KCNN4 (0.41) | POLBCYP3A4CYP2C9LMNAHSP90AA1 | |
| SCHEMBL31294683 | 0.74 | MAPT (0.41) | MAPTRAB9APOLBCYP3A4CYP2C9 | |
| SCHEMBL405869 | 0.72 | KCNN4 (0.46) | CYP3A4CYP2C9LMNAHSP90AA1CYP19A1 | |
| SCHEMBL8637486 | 0.72 | MAPT (0.42) | MAPTRAB9APOLBCYP2C9LMNA | |
| SCHEMBL30628314 | 0.71 | MAPT (0.45) | MAPTRAB9APOLBCYP3A4CYP2C9 | |
| SCHEMBL17157482 | 0.71 | MAPT (0.45) | MAPTRAB9APOLBCYP3A4CYP2C9 | |
| SCHEMBL1507033 | 0.70 | KCNN4 (0.43) | CYP3A4CYP2C9LMNAHSP90AA1CYP19A1 | |
| SCHEMBL14398864 | 0.70 | KCNN4 (0.43) | CYP3A4CYP2C9LMNAHSP90AA1CYP19A1 | |
| SCHEMBL29727285 | 0.70 | KCNN4 (0.43) | CYP3A4CYP2C9LMNAHSP90AA1CYP19A1 | |
| SCHEMBL6400375 | 0.70 | KCNN4 (0.49) | RAB9ACYP3A4CYP2C9LMNAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577712-B1 | FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES | DU PONT (US) | 1998-07-29 | — | — | EP | disclosed |
| EP-0503798-A1 | Fungicidal 4-thixooxazolidin-2-ones and 4-iminooxazolindin-2-ones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-16 | — | — | EP | disclosed |