Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637523 | 0.90 | GPR6 (0.34) | AVPR2AVPR1ARAB9AMEN1ALDH1A1 | |
| SCHEMBL7778674 | 0.88 | KMT2A (0.42) | AVPR2AVPR1ARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7781332 | 0.86 | KMT2A (0.39) | AVPR2AVPR1ARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7340721 | 0.85 | AVPR2 (0.39) | AVPR2AVPR1ARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7478475 | 0.83 | CBX7 (0.38) | AVPR2AVPR1ARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7476401 | 0.80 | MEN1 (0.35) | AVPR2AVPR1ARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7780715 | 0.80 | ALDH1A1 (0.39) | AVPR2AVPR1ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7778599 | 0.79 | SIGMAR1 (0.37) | AVPR2AVPR1AMEN1ALDH1A1KMT2A | |
| SCHEMBL7340123 | 0.78 | KMT2A (0.36) | AVPR2AVPR1ARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7340129 | 0.78 | KMT2A (0.36) | AVPR2AVPR1ARAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |