SCHEMBL863754

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL863755	1.00	KDR (0.81)	KDRFGFR4PDGFRARETPDGFRB
	Lenvatinib SCHEMBL864638	0.89	FGFR4 (1.00)	KDRFGFR4PDGFRARETPDGFRB
	Lenvatinib SCHEMBL29372021	0.89	FGFR4 (1.00)	KDRFGFR4PDGFRARETPDGFRB
	Lenvatinib SCHEMBL29349806	0.89	FGFR4 (1.00)	KDRFGFR4PDGFRARETPDGFRB
	SCHEMBL12673521	0.89	KDR (0.64)	KDRFGFR4PDGFRARETPDGFRB
	SCHEMBL23366513	0.89	KDR (0.83)	KDRFGFR4PDGFRARETPDGFRB
	SCHEMBL1889145	0.89	FGFR4 (0.78)	KDRFGFR4PDGFRARETPDGFRB
	SCHEMBL1889146	0.89	FGFR4 (0.78)	KDRFGFR4PDGFRARETPDGFRB
	Lenvatinib SCHEMBL1389214	0.89	FGFR4 (0.98)	KDRFGFR4PDGFRARETPDGFRB
	SCHEMBL863668	0.86	KDR (0.79)	KDRFGFR4PDGFRARETPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.