SCHEMBL8637540

SCHEMBL8637540

CC(=O)OC(CCl)c1ccsc1S(N)(=O)=O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.33
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8640193 0.86 CA2 (0.33) CA2CA12CA1CA7CA9
SCHEMBL8640306 0.82 KDM4E (0.34) CA2CA12CA1CA9
SCHEMBL9020904 0.75 CA2 (0.33) CA2
SCHEMBL8640399 0.75 CA2 (0.30) CA2CA12CA1CA9
SCHEMBL8642351 0.73 GAA (0.48)
SCHEMBL9020911 0.72 CA2 (0.33) CA2
SCHEMBL9214487 0.72 ALDH1A1 (0.34) CA2CA12CA1CA7CA9
SCHEMBL7911383 0.71 GAA (0.46) CA2CA12CA1CA7CA9
SCHEMBL8637572 0.69 KDM4E (0.32) CA2CA12CA1CA9
SCHEMBL8642438 0.69 CA2 (0.32) CA2CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5726127-A Thiophenesulfonylurea derivatives and herbicidal composition containing the same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1998-03-10 US claimed
EP-0728133-A1 NOVEL THIOPHENESULFONYLUREA DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1996-08-28 EP claimed
WO-1995013276-A1 NOVEL THIOPHENESULFONYLUREA DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-05-18 WO claimed
US-5726127-A Thiophenesulfonylurea derivatives and herbicidal composition containing the same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1998-03-10 US disclosed
EP-0728133-A1 NOVEL THIOPHENESULFONYLUREA DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1996-08-28 EP disclosed
WO-1995013276-A1 NOVEL THIOPHENESULFONYLUREA DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-05-18 WO disclosed