Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.42 |
| ▸ | GSK3B | P49841 | 6/20 | 0.42 |
| ▸ | CDK4 | P11802 | 4/20 | 0.41 |
| ▸ | CCND1 | P24385 | 4/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.38 |
| ▸ | PRKCG | P05129 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896263 | 0.75 | PPOX (0.46) | PARP1GSK3BCDK4CCND1CCNA2 | |
| SCHEMBL2114118 | 0.75 | GSK3B (0.57) | PARP1GSK3BCDK4CCND1CCNA2 | |
| SCHEMBL11248196 | 0.75 | GSK3B (0.45) | PARP1GSK3BCDK4CCND1CCNA2 | |
| SCHEMBL338831 | 0.75 | PARP1 (0.51) | PARP1GSK3BCDK4CCND1CCNA2 | |
| SCHEMBL15059660 | 0.75 | PARP1 (0.44) | PARP1GSK3BCDK4CCND1CCNA2 | |
| SCHEMBL7541755 | 0.74 | TDP1 (0.40) | MCL1MEN1KMT2ABLMTDP1 | |
| SCHEMBL11310333 | 0.73 | ERN1 (0.41) | PARP1GSK3BCDK4CCND1CCNA2 | |
| SCHEMBL11903054 | 0.72 | CDK4 (0.55) | PARP1GSK3BCDK4CCND1CCNA2 | |
| SCHEMBL16489189 | 0.72 | PPOX (0.43) | PARP1GSK3BMEN1KMT2AMAPT | |
| Ethane SCHEMBL11238275 | 0.72 | PARP1 (0.49) | PARP1GSK3BCDK4CCND1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824559-A | Method of analyzing 5-hydroxyindoles and catecholamines, and a device for performing the same | LABORATORY OF MOLECULAR BIOPHOTONICS (JP) | 1998-10-20 | — | — | US | disclosed |