SCHEMBL11248196

SCHEMBL11248196

O=C1NC(=O)c2c1cc(O)c1ccccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 3/20 0.45
PARP1 P09874 3/20 0.44
GLI1 P08151 1/20 0.44
GLI2 P10070 1/20 0.44
PRKCA P17252 2/20 0.44
EGFR P00533 1/20 0.44
CDK5 Q00535 3/20 0.43
CDK5R1 Q15078 3/20 0.43
GSK3A P49840 2/20 0.43
CHEK1 O14757 5/20 0.43
WEE1 P30291 3/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA9 Q16790 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
PPOX P50336 1/20 0.41
ROCK2 O75116 2/20 0.41
CDK4 P11802 2/20 0.40
CCND1 P24385 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7896263 0.78 PPOX (0.46) GSK3BPARP1PRKCACDK5CDK5R1
SCHEMBL2114118 0.78 GSK3B (0.57) GSK3BPARP1PRKCACDK5CDK5R1
SCHEMBL338831 0.78 PARP1 (0.51) GSK3BPARP1PRKCAEGFRCDK5
Ethane SCHEMBL11764200 0.77 CASP3 (0.44) GSK3BCDK5CDK5R1WEE1CDK4
SCHEMBL11903054 0.75 CDK4 (0.55) GSK3BPARP1PRKCAEGFRCDK5
SCHEMBL9006264 0.75 EGFR (0.46) GSK3BPARP1PRKCAEGFRCDK5
Ethane SCHEMBL11238275 0.75 PARP1 (0.49) GSK3BPARP1PRKCACDK5CDK5R1
SCHEMBL6101809 0.75 NQO1 (0.58) GSK3BPARP1GLI1GLI2PRKCA
SCHEMBL8637609 0.75 PARP1 (0.42) GSK3BPARP1PRKCAEGFRCDK5
SCHEMBL15059660 0.74 PARP1 (0.44) GSK3BPARP1PRKCAEGFRCDK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0023666-B1 ANTHRAQUINONE-AZOMETHINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AS WELL AS A PROCESS FOR PIGMENTING ORGANIC MACROMOLECULAR MATERIALS BAYER AG (DE) 1982-10-13 EP claimed
EP-0023666-A1 Anthraquinone-azomethine compounds, process for their preparation as well as a process for pigmenting organic macromolecular materials BAYER AG (DE) 1981-02-11 EP claimed
EP-0023666-B1 ANTHRAQUINONE-AZOMETHINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AS WELL AS A PROCESS FOR PIGMENTING ORGANIC MACROMOLECULAR MATERIALS BAYER AG (DE) 1982-10-13 EP disclosed
US-4323670-A Anthraquinone-azomethine compounds, processes for their preparation and processes for pigmenting organic macromolecular substances BAYER AKTIENGESELLSCHAFT (DE) 1982-04-06 US disclosed
EP-0023666-A1 Anthraquinone-azomethine compounds, process for their preparation as well as a process for pigmenting organic macromolecular materials BAYER AG (DE) 1981-02-11 EP disclosed
US-4235598-A FOR DYEING POLYESTER FIBERS BAYER AKTIENGESELLSCHAFT (DE) 1980-11-25 US disclosed
US-4057539-A DYES, COLORFASTNESS MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1977-11-08 US disclosed