SCHEMBL8637841

SCHEMBL8637841

O=S(=O)(O)c1cc(Nc2cc(Oc3ccc4ccccc4c3)nc(Cl)n2)ccc1-c1ccc(Nc2cc(Oc3ccc4ccccc4c3)nc(Cl)n2)cc1S(=O)(=O)O.[NaH].[NaH]

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 1/20 0.39
▸ KDR P35968 9/20 0.37
▸ PLA2G7 Q13093 1/20 0.36
▸ PARG Q86W56 2/20 0.36
▸ HPGDS O60760 1/20 0.35
▸ SNCA P37840 1/20 0.34
▸ PGR P06401 1/20 0.34
▸ CTDSP1 Q9GZU7 1/20 0.34
▸ CHAT P28329 2/20 0.34
▸ USP2 O75604 1/20 0.34
▸ APEX1 P27695 1/20 0.34
▸ ENPP3 O14638 1/20 0.33
▸ ENPP1 P22413 1/20 0.33
▸ LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9454000 0.99 PPARG (0.39) PPARGKDRPLA2G7PARGHPGDS
SCHEMBL8637879 0.98 PPARG (0.39) PPARGKDRPLA2G7PARGHPGDS
SCHEMBL8637860 0.88 PPARG (0.39) PPARGPLA2G7PGRUSP2APEX1
SCHEMBL8014438 0.84 KDR (0.41) PPARGKDRPLA2G7PARGHPGDS
SCHEMBL9069786 0.83 KDR (0.41) PPARGKDRPLA2G7PARGHPGDS
SCHEMBL9551807 0.82 KDR (0.41) PPARGKDRPLA2G7PARGHPGDS
SCHEMBL8574794 0.78 ENPP2 (0.38) PPARGKDRPLA2G7SNCAPGR
SCHEMBL13295076 0.78 ENPP2 (0.38) PPARGKDRPLA2G7SNCAPGR
SCHEMBL12842815 0.78 KDR (0.44) PPARGKDRPLA2G7SNCAPGR
SCHEMBL9551804 0.77 PLA2G7 (0.38) PPARGKDRPLA2G7SNCAPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0481333-B1 A silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1998-08-12 — — EP disclosed
EP-0421452-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1996-06-19 — — EP disclosed
US-5288604-A Containing sensitizing cyanine dye; high infrared sensitivity FUJI PHOTO FILM CO., LTD. (JP) 1994-02-22 — — US disclosed
EP-0313022-B1 SILVER HALIDE PHOTOSENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1993-03-31 — — EP disclosed
US-5187053-A Storage stability FUJI PHOTO FILM CO., LTD. (JP) 1993-02-16 — — US disclosed
US-5176993-A Layer containing a nitrogen-heterocyclic compound, high silver chloride and a red-sensitive sensitizer dye; high speed development; high photosensitivity; storage stability FUJI PHOTO FILM CO., LTD. (JP) 1993-01-05 — — US disclosed
US-5137803-A Sensitizing desalted silver chlorobromide grains in the presence of a nucleic acid or degradation product FUJI PHOTO FILM CO., LTD. (JP) 1992-08-11 — — US disclosed
EP-0481333-A1 A silver halide color photographic material Fuji Photo Film Co., Ltd. (JP) 1992-04-22 — — EP disclosed
EP-0313021-B1 SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1991-04-10 — — EP disclosed
US-4939080-A Silver halide photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1990-07-03 — — US disclosed
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