SCHEMBL8637879

SCHEMBL8637879

O=S(=O)(O)c1cc(Nc2cc(Oc3ccc4ccccc4c3)nc(Cl)n2)ccc1-c1ccc(Nc2cc(Oc3ccc4ccccc4c3)nc(Cl)n2)cc1S(=O)(=O)O.[Na].[Na]

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 1/20 0.39
▸ PLA2G7 Q13093 2/20 0.39
▸ SNCA P37840 1/20 0.37
▸ PGR P06401 1/20 0.37
▸ KDR P35968 10/20 0.37
▸ CHAT P28329 2/20 0.36
▸ USP2 O75604 1/20 0.36
▸ APEX1 P27695 1/20 0.36
▸ PARG Q86W56 1/20 0.36
▸ HPGDS O60760 1/20 0.35
▸ ENPP3 O14638 1/20 0.35
▸ ENPP1 P22413 1/20 0.35
▸ CTDSP1 Q9GZU7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9454000 0.99 PPARG (0.39) PPARGPLA2G7SNCAPGRKDR
SCHEMBL8637841 0.98 PPARG (0.39) PPARGPLA2G7SNCAPGRKDR
SCHEMBL8637860 0.88 PPARG (0.39) PPARGPLA2G7PGRUSP2APEX1
SCHEMBL9551807 0.84 KDR (0.41) PPARGPLA2G7SNCAPGRKDR
SCHEMBL9069786 0.83 KDR (0.41) PPARGPLA2G7KDRCHATUSP2
SCHEMBL8014438 0.82 KDR (0.41) PPARGPLA2G7KDRCHATUSP2
SCHEMBL9551804 0.79 PLA2G7 (0.38) PPARGPLA2G7SNCAPGRKDR
SCHEMBL13295076 0.78 ENPP2 (0.38) PPARGPLA2G7SNCAPGRKDR
SCHEMBL12842815 0.78 KDR (0.44) PPARGPLA2G7SNCAPGRKDR
SCHEMBL8574794 0.78 ENPP2 (0.38) PPARGPLA2G7SNCAPGRKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0481333-B1 A silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1998-08-12 — — EP disclosed
EP-0313022-B1 SILVER HALIDE PHOTOSENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1993-03-31 — — EP disclosed
EP-0481333-A1 A silver halide color photographic material Fuji Photo Film Co., Ltd. (JP) 1992-04-22 — — EP disclosed
US-4939080-A Silver halide photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1990-07-03 — — US disclosed
Send feedback