Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 2/20 | 0.39 |
| ▸ | P2RY12 known ✓ | Q9H244 | 5/20 | 0.38 |
| ▸ | P2RY2 known ✓ | P41231 | 7/20 | 0.37 |
| ▸ | P2RY1 known ✓ | P47900 | 2/20 | 0.37 |
| ▸ | P2RY4 known ✓ | P51582 | 5/20 | 0.37 |
| ▸ | P2RY6 known ✓ | Q15077 | 2/20 | 0.37 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.36 |
| ▸ | FUT8 | Q9BYC5 | 2/20 | 0.37 |
| ▸ | ENTPD1 | P49961 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9454000 | 0.89 | PPARG (0.39) | PPARGPGRPLA2G7USP2LMNA | |
| SCHEMBL8637841 | 0.88 | PPARG (0.39) | PPARGPGRPLA2G7USP2LMNA | |
| SCHEMBL8637879 | 0.88 | PPARG (0.39) | PPARGPGRPLA2G7USP2APEX1 | |
| SCHEMBL8014411 | 0.84 | PPARG (0.39) | PPARGP2RY12P2RY2P2RY1FUT8 | |
| SCHEMBL8003076 | 0.79 | RAD51 (0.47) | PPARGP2RY2ENTPD1PGRPLA2G7 | |
| SCHEMBL8943258 | 0.75 | RAD51 (0.44) | MEN1USP2CYP3A4MAPTHPGD | |
| SCHEMBL9587946 | 0.74 | PPARG (0.32) | PPARGPGRPLA2G7 | |
| SCHEMBL9069786 | 0.73 | KDR (0.41) | PPARGPLA2G7USP2MAPTAPEX1 | |
| SCHEMBL9551807 | 0.72 | KDR (0.41) | PPARGPGRPLA2G7USP2MAPT | |
| SCHEMBL8014438 | 0.72 | KDR (0.41) | PPARGPLA2G7USP2MAPTAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481333-B1 | A silver halide color photographic material | FUJI PHOTO FILM CO LTD (JP) | 1998-08-12 | — | — | EP | disclosed |
| EP-0421452-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1996-06-19 | — | — | EP | disclosed |
| US-5288604-A | Containing sensitizing cyanine dye; high infrared sensitivity | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0313022-B1 | SILVER HALIDE PHOTOSENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |
| US-5187053-A | Storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1993-02-16 | — | — | US | disclosed |
| US-5176993-A | Layer containing a nitrogen-heterocyclic compound, high silver chloride and a red-sensitive sensitizer dye; high speed development; high photosensitivity; storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| US-5137803-A | Sensitizing desalted silver chlorobromide grains in the presence of a nucleic acid or degradation product | FUJI PHOTO FILM CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0481333-A1 | A silver halide color photographic material | Fuji Photo Film Co., Ltd. (JP) | 1992-04-22 | — | — | EP | disclosed |
| EP-0313021-B1 | SILVER HALIDE PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1991-04-10 | — | — | EP | disclosed |
| US-4939080-A | Silver halide photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-07-03 | — | — | US | disclosed |
| EP-0368356-A1 | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-16 | — | — | EP | disclosed |