Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417423 | 0.91 | RIPK1 (0.36) | RIPK1 | |
| SCHEMBL8631046 | 0.87 | PLA2G2A (0.33) | RIPK1TLR8TLR7CDC25BMYC | |
| SCHEMBL8421429 | 0.83 | AGTR1 (0.34) | — | |
| SCHEMBL8419127 | 0.82 | AGTR1 (0.34) | — | |
| SCHEMBL8422200 | 0.78 | AGTR1 (0.33) | — | |
| SCHEMBL8417984 | 0.78 | AGTR1 (0.34) | — | |
| SCHEMBL8417384 | 0.77 | PLA2G2A (0.36) | — | |
| SCHEMBL8417941 | 0.74 | PPARG (0.35) | — | |
| SCHEMBL8417421 | 0.74 | AGTR1 (0.34) | — | |
| SCHEMBL8417914 | 0.74 | PDCD1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705517-A | ANGIOTENSIN II ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-06 | — | — | US | disclosed |