Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639097 | 0.90 | MMP9 (0.48) | LMNAHPGDDGAT1MMP3MEN1 | |
| SCHEMBL8639821 | 0.90 | MMP9 (0.48) | LMNAHPGDDGAT1MMP3MEN1 | |
| SCHEMBL8642069 | 0.87 | PTPN1 (0.41) | LMNAHPGDSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8644830 | 0.86 | MMP9 (0.42) | LMNAHPGDMMP3MEN1KMT2A | |
| SCHEMBL8638173 | 0.86 | MMP9 (0.42) | LMNAHPGDMMP3MEN1KMT2A | |
| SCHEMBL8755957 | 0.84 | LTA4H (0.44) | LMNAHPGDDGAT1MMP3MEN1 | |
| SCHEMBL8637613 | 0.81 | MME (0.55) | HPGDMMP3MMP9MMP1ACE | |
| SCHEMBL8638354 | 0.79 | LTA4H (0.45) | DGAT1MMP3MEN1KMT2AMMP9 | |
| Lithium Ion SCHEMBL8637659 | 0.79 | MMP2 (0.44) | DGAT1MMP3MEN1KMT2AMMP9 | |
| SCHEMBL8639883 | 0.79 | LTA4H (0.45) | DGAT1MMP3MEN1KMT2AMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766694-B1 | PEPTIDE DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 1998-08-05 | — | — | EP | disclosed |