SCHEMBL8638622

SCHEMBL8638622

CCCc1cc(F)c(CCc2cc(F)c(CCc3cc(F)c(F)c(F)c3)c(F)c2)c(F)c1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.34
RIPK1 Q13546 1/20 0.33
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
PKM P14618 2/20 0.31
TP53 P04637 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8640226 0.89 NPC1 (0.30) NPC1RAB9APKMTP53SMN1; SMN2
SCHEMBL6793126 0.89 RIPK1 (0.38) RIPK1NPC1RAB9AHPGDMAPK1
SCHEMBL17487642 0.86 CTSL (0.33)
SCHEMBL17487802 0.82 RARB (0.37) NPC1RAB9ACNR1CNR2PKM
SCHEMBL13002670 0.81 DAO (0.45) TAAR1
SCHEMBL8474649 0.81
SCHEMBL16105773 0.79 CES2 (0.39) TAAR1RIPK1HPGDMAOB
SCHEMBL17487588 0.78 CTSL (0.37)
SCHEMBL7228753 0.78 TUBB1 (0.33)
SCHEMBL7228749 0.78 TUBB1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10059881-A None JP disclosed
JP-H1059881-A LIQUID CRYSTALLINE COMPOUND WITH EXTREMELY HIGH DIELECTRIC CONSTANT ANISOTROPY DAINIPPON INK & CHEM INC 1998-03-03 JP disclosed