SCHEMBL8640226

SCHEMBL8640226

CCCc1cc(F)c(CCc2cc(F)c(-c3cc(F)c(F)c(F)c3)c(F)c2)c(F)c1

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.30
TP53 P04637 1/20 0.30
PKM P14618 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8638622 0.89 TAAR1 (0.34) NPC1TP53PKMRAB9ASMN1; SMN2
SCHEMBL17070822 0.81 RAPGEF4 (0.36) NPC1TP53PKMRAB9ASMN1; SMN2
SCHEMBL15744562 0.80 DAO (0.32)
SCHEMBL15744511 0.80 DAO (0.32)
SCHEMBL15744983 0.80 DAO (0.32)
SCHEMBL15744610 0.80
SCHEMBL6793126 0.80 RIPK1 (0.38) NPC1TP53PKMRAB9ASMN1; SMN2
SCHEMBL17487802 0.79 RARB (0.37) NPC1TP53PKMRAB9ASMN1; SMN2
SCHEMBL8474649 0.78
SCHEMBL15965523 0.78 RARB (0.42) NPC1TP53PKMRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10059882-A None JP disclosed
US-7198827-B1 Nematic liquid crystal composition and liquid crystal display device using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-04-03 US disclosed
US-7198827-B1 Nematic liquid crystal composition and liquid crystal display device using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-04-03 US disclosed
JP-H1059882-A FLUOROBIPHENYL DERIVATIVE DAINIPPON INK & CHEM INC 1998-03-03 JP disclosed