Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM6B | O15054 | 3/20 | 0.35 |
| ▸ | KDM4A | O75164 | 3/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.35 |
| ▸ | KDM3B | Q7LBC6 | 3/20 | 0.35 |
| ▸ | HIF1AN | Q9NWT6 | 3/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 3/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462849 | 0.76 | CNR1 (0.47) | ALDH1A1LMNASMN1; SMN2CYP2C19KAT8 | |
| SCHEMBL7019137 | 0.70 | KDM5A (0.38) | ALDH1A1KDM5BLMNAKDM4EMEN1 | |
| SCHEMBL8638685 | 0.70 | KDM4E (0.38) | ALDH1A1LMNAKDM4EMEN1RECQL | |
| SCHEMBL21327359 | 0.68 | LMNA (0.33) | ALDH1A1LMNAKDM4ERECQLKMT2A | |
| SCHEMBL21327360 | 0.68 | LMNA (0.33) | ALDH1A1LMNAKDM4ERECQLKMT2A | |
| Hydrochloric Acid SCHEMBL15559929 | 0.67 | CNR2 (0.46) | ALDH1A1 | |
| SCHEMBL27660819 | 0.65 | OPRM1 (0.34) | ALDH1A1LMNA | |
| Acetic Acid SCHEMBL29271967 | 0.65 | CYP17A1 (0.42) | KDM4E | |
| SCHEMBL22748596 | 0.65 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2CYP2C19RARB | |
| SCHEMBL21979692 | 0.64 | L3MBTL1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |