Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 4/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.32 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640485 | 0.90 | NR3C1 (0.36) | ALDH1A1NR3C1CASRTUBB4ATUBB | |
| SCHEMBL8641470 | 0.86 | LTA4H (0.43) | CASRMMP9MMP13KMT2ANPC1 | |
| SCHEMBL8641306 | 0.83 | ALDH1A1 (0.35) | ALDH1A1NR3C1ERN1SMN1; SMN2 | |
| SCHEMBL8641037 | 0.82 | NR3C1 (0.39) | NR3C1CASRTUBB4ATUBBTUBA3C | |
| SCHEMBL8637521 | 0.73 | ALDH1A1 (0.45) | ALDH1A1NR3C1CASRMMP9MMP13 | |
| SCHEMBL18387780 | 0.68 | IDO1 (0.45) | ALDH1A1CASRMMP9MMP13IDO1 | |
| SCHEMBL5521328 | 0.66 | IDO1 (0.47) | ALDH1A1CASRIDO1HTTSMN1; SMN2 | |
| SCHEMBL8641236 | 0.66 | NR3C1 (0.37) | ALDH1A1NR3C1CASRIDO1GLA | |
| SCHEMBL8639144 | 0.66 | ALDH1A1 (0.42) | ALDH1A1NR3C1CASRMMP9MMP13 | |
| SCHEMBL8637517 | 0.66 | ALDH1A1 (0.42) | ALDH1A1NR3C1CASRMMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516257-B1 | Phenylbenzo[b]furans and -thiophenes, procedures for their preparation, and pharmaceutical compositions containing the same | SCHERING AG (DE) | 1998-08-05 | — | — | EP | disclosed |
| US-5470854-A | Antiestrogens | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-11-28 | — | — | US | disclosed |
| WO-1992021669-A1 | 2-PHENYLBENZO[B]FURANS AND THIOPHENES, METHODS OF PREPARING THEM AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-12-10 | — | — | WO | disclosed |
| EP-0516257-A1 | Phenylbenzo[b]furans and -thiophenes, procedures for their preparation, and pharmaceutical compositions containing the same | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-12-02 | — | — | EP | disclosed |