Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639151 | 0.83 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2NR3C1ERN1 | |
| SCHEMBL8640485 | 0.81 | NR3C1 (0.36) | ALDH1A1CYP3A4SMN1; SMN2MAPTCYP2C19 | |
| SCHEMBL8641470 | 0.79 | LTA4H (0.43) | SMN1; SMN2CYP2C19 | |
| SCHEMBL8641037 | 0.75 | NR3C1 (0.39) | NR3C1ERN1 | |
| SCHEMBL8641291 | 0.71 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TP53ALOX15TSHR | |
| SCHEMBL8639442 | 0.67 | TDP1 (0.34) | ALDH1A1CYP3A4TP53ALOX15TSHR | |
| SCHEMBL6056697 | 0.65 | ALOX15 (0.58) | ALDH1A1CYP3A4TP53ALOX15TSHR | |
| SCHEMBL8076016 | 0.63 | ALOX15 (0.56) | ALDH1A1CYP3A4TP53ALOX15TSHR | |
| SCHEMBL8076317 | 0.63 | ALOX15 (0.56) | ALDH1A1CYP3A4TP53ALOX15TSHR | |
| SCHEMBL8077879 | 0.63 | ALOX15 (0.56) | ALDH1A1CYP3A4TP53ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516257-B1 | Phenylbenzo[b]furans and -thiophenes, procedures for their preparation, and pharmaceutical compositions containing the same | SCHERING AG (DE) | 1998-08-05 | — | — | EP | disclosed |
| US-5470854-A | Antiestrogens | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-11-28 | — | — | US | disclosed |
| WO-1992021669-A1 | 2-PHENYLBENZO[B]FURANS AND THIOPHENES, METHODS OF PREPARING THEM AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-12-10 | — | — | WO | disclosed |
| EP-0516257-A1 | Phenylbenzo[b]furans and -thiophenes, procedures for their preparation, and pharmaceutical compositions containing the same | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-12-02 | — | — | EP | disclosed |