Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1924321 | 0.86 | PLOD2 (0.59) | PLOD2MAPTPOLBRAB9ACES2 | |
| SCHEMBL2080446 | 0.79 | CES2 (0.49) | MAPTPOLBRAB9ACES2CES1 | |
| SCHEMBL1925762 | 0.77 | CES2 (0.44) | MAPTHTTPOLBRAB9ACES2 | |
| SCHEMBL25415875 | 0.77 | MAPT (0.47) | MAPTPOLBRAB9ACES2CES1 | |
| SCHEMBL1925754 | 0.74 | CES2 (0.41) | MAPTHTTPOLBRAB9ACES2 | |
| SCHEMBL5117814 | 0.74 | PLOD2 (0.59) | PLOD2MAPTHTTPOLBCES2 | |
| SCHEMBL9234534 | 0.74 | CES2 (0.46) | MAPTHTTPOLBRAB9ACES2 | |
| SCHEMBL2031624 | 0.73 | MAPT (0.44) | MAPTPOLBRAB9ACES2CES1 | |
| SCHEMBL2031630 | 0.73 | MAPT (0.44) | MAPTPOLBRAB9ACES2CES1 | |
| SCHEMBL367075 | 0.73 | TSHR (0.57) | MAPTPOLBRAB9ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753688-A | ANTIINFLAMMATORY | TALLEY JOHN J (US) | 1998-05-19 | — | — | US | disclosed |