Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | CCKBR | P32239 | 1/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11651629 | 0.85 | KMT2A (0.76) | KMT2AMEN1GAAMAPTHSD17B10 | |
| SCHEMBL7044712 | 0.84 | HPGD (0.53) | KMT2AMEN1GAAMAPTHSD17B10 | |
| SCHEMBL8635136 | 0.81 | NPC1 (0.52) | KMT2AMEN1MAPTHSD17B10HTT | |
| SCHEMBL4422153 | 0.80 | HPGD (0.74) | KMT2AMEN1GAAMAPTHPGD | |
| SCHEMBL8616731 | 0.80 | CCKBR (0.51) | KMT2AMEN1GAAMAPTHSD17B10 | |
| SCHEMBL8616366 | 0.80 | CCKBR (0.51) | KMT2AMEN1GAAMAPTHSD17B10 | |
| SCHEMBL9603352 | 0.78 | CCKBR (0.49) | KMT2AMEN1GAAMAPTHSD17B10 | |
| SCHEMBL5398736 | 0.78 | HPGD (0.53) | KMT2AMEN1GAAHPGDALDH1A1 | |
| SCHEMBL10158776 | 0.77 | KMT2A (1.00) | KMT2AMEN1GAAMAPTHSD17B10 | |
| SCHEMBL8638848 | 0.75 | CCKBR (0.58) | HSD17B10HPGDALDH1A1CASP7CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558104-B1 | 1,5-Benzodiazepine derivatives and their use in medicine | GLAXO WELLCOME SPA (IT) | 1998-07-29 | — | — | EP | disclosed |
| US-5637697-A | ANTAGONIST TO GASTRIN AND(OR) CHLOROCYSTOKININ | GLAXO SPA (IT) | 1997-06-10 | — | — | US | disclosed |
| US-5580895-A | GASTROINTESTINAL OR CENTRAL NERVOUS SYSTEM DISORDERS | GLAXO SPA (IT) | 1996-12-03 | — | — | US | disclosed |
| EP-0558104-A1 | 1,5-Benzodiazepine derivatives and their use in medicine | GLAXO S.p.A. (IT) | 1993-09-01 | — | — | EP | disclosed |