Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640412 | 0.95 | REN (0.46) | RENACELMNAPDE3AMME | |
| SCHEMBL8644979 | 0.91 | REN (0.42) | RENMMP3ACELMNAMME | |
| SCHEMBL8638062 | 0.91 | REN (0.42) | RENMMP3ACELMNAMME | |
| SCHEMBL8756920 | 0.89 | REN (0.47) | RENMMP3ACELMNAMME | |
| SCHEMBL8645002 | 0.88 | REN (0.41) | RENACELMNAMME | |
| SCHEMBL8642399 | 0.88 | NPC1 (0.39) | RENALDH1A1CTSKACEMME | |
| SCHEMBL8638508 | 0.88 | NPC1 (0.39) | RENALDH1A1CTSKACEMME | |
| SCHEMBL8641870 | 0.87 | MME (0.48) | MMP3ALDH1A1CTSKMMEKMT2A | |
| SCHEMBL8636757 | 0.87 | MME (0.50) | ACELMNAPDE3AMMEABCB11 | |
| SCHEMBL8639879 | 0.83 | ACE (0.42) | ACELMNAPDE3AMMEABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766694-B1 | PEPTIDE DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 1998-08-05 | — | — | EP | disclosed |