Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636757 | 0.88 | MME (0.50) | ACELMNAABCB11SMN1; SMN2MEN1 | |
| SCHEMBL8640412 | 0.87 | REN (0.46) | ACELMNAABCB11SMN1; SMN2MEN1 | |
| SCHEMBL8640345 | 0.83 | MME (0.53) | ACESMN1; SMN2MEN1KMT2AMME | |
| SCHEMBL8640416 | 0.83 | MME (0.53) | ACESMN1; SMN2MEN1KMT2AMME | |
| SCHEMBL8639909 | 0.83 | REN (0.43) | ACELMNAABCB11SMN1; SMN2MEN1 | |
| SCHEMBL8638062 | 0.83 | REN (0.42) | ACELMNAABCB11SMN1; SMN2MEN1 | |
| SCHEMBL8644979 | 0.83 | REN (0.42) | ACELMNAABCB11SMN1; SMN2MEN1 | |
| SCHEMBL8645002 | 0.81 | REN (0.41) | ACELMNAMME | |
| SCHEMBL8756920 | 0.80 | REN (0.47) | ACELMNAABCB11SMN1; SMN2MEN1 | |
| SCHEMBL8638508 | 0.79 | NPC1 (0.39) | ACEMEN1KMT2AMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766694-B1 | PEPTIDE DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 1998-08-05 | — | — | EP | disclosed |