Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642399 | 1.00 | NPC1 (0.39) | NPC1RAB9ACTSKRENCTSB | |
| SCHEMBL8640412 | 0.92 | REN (0.46) | RENMEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL8638062 | 0.90 | REN (0.42) | RENMEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL8644979 | 0.90 | REN (0.42) | RENMEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL8639909 | 0.88 | REN (0.43) | NPC1RAB9ACTSKRENMEN1 | |
| SCHEMBL8639130 | 0.87 | ANPEP (0.44) | CTSBMEN1HTTKMT2ATAS1R3 | |
| SCHEMBL8756920 | 0.85 | REN (0.47) | RENMEN1KMT2AACEMME | |
| SCHEMBL8645002 | 0.85 | REN (0.41) | RENACEMME | |
| SCHEMBL8636757 | 0.83 | MME (0.50) | RAB9AMEN1KMT2AACEMME | |
| SCHEMBL8640058 | 0.82 | CTSB (0.40) | CTSKCTSBMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766694-B1 | PEPTIDE DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 1998-08-05 | — | — | EP | disclosed |