Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16521129 | 0.86 | RAPGEF4 (0.34) | RAPGEF4 | |
| SCHEMBL8640226 | 0.81 | NPC1 (0.30) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL6793126 | 0.81 | RIPK1 (0.38) | RAPGEF4PTGS2NPC1TP53PKM | |
| SCHEMBL16488492 | 0.76 | RARB (0.42) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL15965523 | 0.76 | RARB (0.42) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL21448653 | 0.75 | NPC1 (0.38) | FFAR4PTGS2NPC1TP53PKM | |
| SCHEMBL9255718 | 0.74 | NPC1 (0.33) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL17108404 | 0.74 | RARB (0.40) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL13342413 | 0.74 | FFAR4 (0.38) | RAPGEF4FFAR4PTGS1PTGS2NPC1 | |
| SCHEMBL29295181 | 0.74 | FFAR4 (0.38) | RAPGEF4FFAR4PTGS1PTGS2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9441160-B2 | Fluorobiphenyl-containing composition | DIC CORPORATION (JP) | 2016-09-13 | — | — | US | disclosed |
| US-20150376501-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME | DIC CORPORATION (JP) | 2015-12-31 | — | — | US | disclosed |
| US-20150291881-A1 | FLUOROBIPHENYL-CONTAINING COMPOSITION | DIC CORPORATION (JP) | 2015-10-15 | — | — | US | disclosed |
| US-20150252263-A1 | FLUOROBIPHENYL-CONTAINING COMPOSITION | DIC CORPORATION (JP) | 2015-09-10 | — | — | US | disclosed |