SCHEMBL8640528

SCHEMBL8640528

CCCC1CCC(C2C=CCCC2=O)CC1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 2/20 0.43
CYP2C9 P11712 1/20 0.33
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8635869 0.91 CYP1A2 (0.37) TLR4LMNAMAPT
SCHEMBL8640047 0.90 CYP1A2 (0.38) TLR4CYP2C9ALDH1A1
SCHEMBL8635030 0.87 TLR4 (0.31) TLR4
SCHEMBL3351382 0.71 NFKB1 (0.30)
SCHEMBL1666552 0.69 TLR4 (0.51) TLR4CYP2C9ALDH1A1LMNAMAPT
SCHEMBL1666553 0.69 TLR4 (0.51) TLR4CYP2C9ALDH1A1LMNAMAPT
SCHEMBL8215701 0.69 TLR4 (0.51) TLR4CYP2C9ALDH1A1LMNAMAPT
SCHEMBL10985227 0.67 CA1 (0.30)
SCHEMBL10022182 0.67 TLR4 (0.44) TLR4CYP2C9ALDH1A1LMNAMAPT
SCHEMBL15203851 0.67 TLR4 (0.44) TLR4CYP2C9ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0571652-B1 Liquid crystalline substituted dihydrobenzene derivatives CITIZEN WATCH CO LTD (JP) 1998-08-05 EP disclosed
US-5342546-A Liquid crystal compositions L.C.C. CONSULTANTS CO., LTD. (JP) 1994-08-30 US disclosed
EP-0571652-A1 Liquid crystalline substituted dihydrobenzene derivatives L.C.C. CONSULTANTS CO., LTD. (JP) 1993-12-01 EP disclosed