Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640744 | 0.89 | HPGD (0.47) | ALDH1A1LMNAMAPTKDM4ETDP1 | |
| SCHEMBL8614423 | 0.86 | CSNK2A2 (0.40) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL8618302 | 0.85 | NPC1 (0.37) | ALDH1A1LMNAMAPTKDM4EMAPK1 | |
| SCHEMBL8617892 | 0.85 | GSK3B (0.45) | ALDH1A1LMNAMAPTKDM4ETDP1 | |
| SCHEMBL8616362 | 0.85 | CLK1 (0.58) | ALDH1A1LMNAMAPTKDM4ECSNK2A2 | |
| SCHEMBL8619553 | 0.83 | GSK3B (0.40) | ALDH1A1LMNAMAPTKDM4ETDP1 | |
| SCHEMBL8619011 | 0.83 | PTGS2 (0.44) | ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL8614425 | 0.75 | PIM1 (0.53) | NPC1RAB9AHPGDPPARGGAA | |
| SCHEMBL8618308 | 0.75 | MTOR (0.47) | KMT2AMEN1HPGDPPARG | |
| SCHEMBL8616364 | 0.74 | PIM1 (0.57) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767121-A | ANTIINFLAMMATORY AND -ARTHRITIC AGENTS; ANTIPYRETICS; ANALGESICS; ADHESION PROTEIN EXPRESSION AND CYCLOXYGENASE AND 5-LIPOXYGENASE INHIBITORS; IMMUNOSUPPRESSANTS AND -MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-16 | — | — | US | disclosed |