Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | MELK | Q14680 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434353 | 0.79 | ALDH1A1 (0.42) | TDP2ALDH1A1PDE3BPDE3A | |
| SCHEMBL16518134 | 0.78 | PARP1 (0.41) | PARP1HTR2AHTR2CPDE3BPDE3A | |
| SCHEMBL8355517 | 0.76 | HTR7 (0.46) | HTR2CALDH1A1HTR6NISCH | |
| SCHEMBL436723 | 0.75 | MAOA (0.41) | TDP2ALDH1A1 | |
| SCHEMBL435076 | 0.75 | ALDH1A1 (0.39) | TDP2ALDH1A1 | |
| SCHEMBL16518151 | 0.74 | PNMT (0.46) | PARP1HTR2AHTR2CHTR6NISCH | |
| SCHEMBL16518127 | 0.74 | PRCP (0.55) | PARP1 | |
| SCHEMBL16518161 | 0.74 | PARP1 (0.39) | PARP1HTR2AHTR2CPDE3BPDE3A | |
| SCHEMBL16492225 | 0.74 | PKN2 (0.51) | PARP1HTR2AHTR2CTDP2PARP10 | |
| SCHEMBL8635851 | 0.74 | HTR2A (0.42) | HTR2AHTR2CHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |