SCHEMBL86418

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL168135	0.89	HSD17B10 (0.59)	KMT2AHSD17B10ALDH1A1L3MBTL1LMNA
	SCHEMBL9251076	0.87	HSD17B10 (0.57)	KMT2AHSD17B10ALDH1A1L3MBTL1LMNA
	SCHEMBL11612809	0.84	KMT2A (0.59)	KMT2AHSD17B10ALDH1A1L3MBTL1LMNA
	SCHEMBL2387794	0.82	NPC1 (0.57)	KMT2AALDH1A1RAB9AMAPTNPC1
	SCHEMBL86139	0.82	ALDH1A1 (0.47)	HSD17B10ALDH1A1L3MBTL1RAB9AMAPT
	SCHEMBL4242570	0.82	ALDH1A1 (0.62)	KMT2AALDH1A1RAB9AMAPTNPC1
	SCHEMBL8652676	0.82	LMNA (0.45)	ALDH1A1L3MBTL1LMNARAB9AMAPT
	SCHEMBL3975016	0.82	NPC1 (0.43)	KMT2AHSD17B10ALDH1A1L3MBTL1LMNA
	SCHEMBL7365104	0.82	ESR1 (0.56)	KMT2AALDH1A1LMNARAB9AMAPT
	SCHEMBL168852	0.82	GSK3B (0.50)	ALDH1A1L3MBTL1RAB9AMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.