Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
| ▸ | BPTF | Q12830 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24681614 | 0.84 | NOTUM (0.41) | FFAR2NOTUMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24681245 | 0.84 | NOTUM (0.41) | FFAR2NOTUMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24681247 | 0.84 | NOTUM (0.41) | FFAR2NOTUMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13113465 | 0.81 | ALDH1A1 (0.38) | LMNAFFAR2HRH3ALDH1A1KDM4E | |
| SCHEMBL10309786 | 0.80 | AGXT (0.40) | FFAR2NOTUM | |
| SCHEMBL24681252 | 0.77 | LMNA (0.52) | LMNAFFAR2BPTFNOTUMCHRNA7 | |
| SCHEMBL4855532 | 0.77 | LMNA (0.52) | LMNAFFAR2BPTFNOTUMCHRNA7 | |
| SCHEMBL24680783 | 0.77 | LMNA (0.52) | LMNAFFAR2BPTFNOTUMCHRNA7 | |
| SCHEMBL29157655 | 0.77 | NOTUM (0.45) | LMNANOTUMALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL29157654 | 0.77 | NOTUM (0.45) | LMNANOTUMALDH1A1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773437-A | UROGENITAL DISORDERS SUCH AS DYSURIA | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |