Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 4/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 14/20 | 0.43 |
| ▸ | CTRC | Q99895 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.40 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13160627 | 1.00 | XIAP (0.46) | XIAPF2PRSS1CMA1CTRC | |
| SCHEMBL864369 | 1.00 | XIAP (0.46) | XIAPF2PRSS1CMA1CTRC | |
| SCHEMBL864371 | 1.00 | XIAP (0.46) | XIAPF2PRSS1CMA1CTRC | |
| SCHEMBL865440 | 0.87 | DPP4 (0.43) | ACE | |
| SCHEMBL865442 | 0.87 | DPP4 (0.43) | ACE | |
| SCHEMBL865441 | 0.87 | DPP4 (0.43) | ACE | |
| SCHEMBL864625 | 0.86 | XIAP (0.46) | XIAPF2PRSS1CMA1CTRC | |
| SCHEMBL864624 | 0.86 | XIAP (0.46) | XIAPF2PRSS1CMA1CTRC | |
| SCHEMBL864626 | 0.86 | XIAP (0.46) | XIAPF2PRSS1CMA1CTRC | |
| SCHEMBL864372 | 0.84 | P2RX7 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077793-A1 | Compounds for the Treatment of Metabolic Disorders | PROSIDION LIMITED (GB) | 2012-03-29 | — | — | US | disclosed |
| EP-2406247-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Prosidion Limited (GB) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010103333-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077793-A1 | Compounds for the Treatment of Metabolic Disorders | GPR119, GPR132, FFAR2 | XIAP 3716/4885F2 3677/4885PRSS1 2411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.