Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA7 | P43166 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ESRRB | O95718 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27402000 | 0.79 | TRPA1 (0.48) | LMNAHSD17B10TRPA1CA12CA1 | |
| SCHEMBL8378255 | 0.79 | TRPA1 (0.48) | LMNAHSD17B10TRPA1CA12CA1 | |
| SCHEMBL8645873 | 0.74 | NPSR1 (0.44) | LMNACA1CA2ESR2MEN1 | |
| SCHEMBL8379723 | 0.73 | GRN (0.45) | LMNAHSD17B10CA12CA1CA2 | |
| SCHEMBL8646849 | 0.73 | LMNA (0.39) | LMNAHSD17B10TRPA1CA12CA1 | |
| SCHEMBL8645782 | 0.71 | LMNA (0.45) | LMNAHSD17B10CA12CA1CA2 | |
| SCHEMBL8383097 | 0.69 | CA12 (0.45) | LMNAHSD17B10CA12CA1CA2 | |
| SCHEMBL9835782 | 0.69 | CA12 (0.45) | LMNAHSD17B10CA12CA1CA2 | |
| SCHEMBL8379546 | 0.67 | PREP (0.36) | LMNATRPA1CA12CA1CA9 | |
| SCHEMBL1673397 | 0.67 | ESR1 (0.44) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726185-A | BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELET AGGREGATION AND CELL TO CELL ADHESION | HOFFMANN-LA ROCHE INC. (US) | 1998-03-10 | — | — | US | disclosed |