Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1673397 | 0.80 | ESR1 (0.44) | NPSR1SMN1; SMN2KMT2ACA1CA2 | |
| SCHEMBL8647573 | 0.76 | NPSR1 (0.45) | NPSR1ALDH1A1CYP1A2SMN1; SMN2MEN1 | |
| SCHEMBL8378255 | 0.75 | TRPA1 (0.48) | MAPTALDH1A1LMNAHTTMEN1 | |
| SCHEMBL27402000 | 0.75 | TRPA1 (0.48) | MAPTALDH1A1LMNAHTTMEN1 | |
| SCHEMBL8644079 | 0.74 | LMNA (0.38) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7512700 | 0.72 | MAPT (0.64) | MAPTALDH1A1CYP1A2LMNAHTT | |
| SCHEMBL6473480 | 0.72 | MAPT (0.49) | MAPTALDH1A1CYP1A2LMNAHTT | |
| SCHEMBL8646849 | 0.72 | LMNA (0.39) | LMNACYP3A4CA1CA2ESR2 | |
| SCHEMBL8382550 | 0.72 | CA2 (0.50) | MAPTSMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL16165182 | 0.70 | ALDH1A1 (0.54) | NPSR1SLC2A1MAPTALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726185-A | BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELET AGGREGATION AND CELL TO CELL ADHESION | HOFFMANN-LA ROCHE INC. (US) | 1998-03-10 | — | — | US | disclosed |